Mitochondrial haplogroups associated with elite Japanese athlete status.

Mitochondrial haplogroups associated with elite Kenyan athlete status.

UNLABELLED The maternal inheritance of mitochondrial DNA (mtDNA) has enabled construction of detailed phylogenies. Analysis of key polymorphisms from these phylogenies allows mtDNA to be assigned to haplogroups, which have been associated with elite endurance performance. PURPOSE To compare the frequencies of mtDNA haplogroups found in elite Kenyan athletes with those in the general Kenyan po...

The champions' mitochondria: is it genetically determined? A review on mitochondrial DNA and elite athletic performance.

Aerobic ATP generation by the mitochondrial respiratory oxidative phosphorylation system (OXPHOS) is a vital metabolic process for endurance exercise. Notably, mitochondrial DNA (mtDNA) codifies 13 of the 83 polypeptides implied in the respiratory chain. As such, there is a strong rationale for identifying an association between mtDNA variants and "aerobic" (endurance) exercise phenotypes. The ...

Mitochondrial Haplogroups Associated with Japanese Parkinson’s Patients

Mitochondrial Haplogroups and Well Defined Populations

Japanese Alzheimer's Disease and Other Complex Disorders Diagnosis Based on Mitochondrial SNP Haplogroups

This paper first explains how the relations between Japanese Alzheimer's disease (AD) patients and their mitochondrial SNP frequencies at individual mtDNA positions examined using the radial basis function (RBF) network and a method based on RBF network predictions and that Japanese AD patients are associated with the haplogroups G2a and N9b1. It then describes a method for the initial diagnosi...